The Cheesy Loaded Meatloaf Casserole is a comfort food classic that brings a delightful twist to traditional meatloaf. This hearty dish, full of rich flavors and topped with a generous amount of cheese, perfectly combines the savory elements of a meatloaf with the creamy goodness of a casserole.
The origins of meatloaf can be traced back to ancient Rome, where it was first documented in the Latin cookbook 'Apicius'. However, the modern version gained popularity in the United States during the Great Depression due to its economical use of ingredients.
Today, the Cheesy Loaded Meatloaf Casserole has evolved to include a variety of ingredients, making it an ideal dish for family gatherings and weeknight dinners. For an in-depth look at the history of meatloaf, you can visit History.com.
Ingredients for Cheesy Loaded Meatloaf Casserole
- 1 1/2 pounds ground beef
- 1 cup breadcrumbs
- 1/2 cup milk
- 1 egg
- 1 teaspoon salt
- 1/2 teaspoon black pepper
- 1 teaspoon garlic powder
- 1 teaspoon onion powder
- 1/2 cup ketchup
- 1 tablespoon Worcestershire sauce
- 2 cups shredded cheddar cheese
- 4 slices of bacon, cooked and crumbled
- 2 cups mashed potatoes
- 1/4 cup chopped green onions

Instructions for Making Cheesy Loaded Meatloaf Casserole
- Preheat your oven to 375°F (190°C).
- In a large bowl, combine the ground beef, breadcrumbs, milk, egg, salt, pepper, garlic powder, and onion powder. Mix until well combined.
- Press the meat mixture into a greased 9×13 inch baking dish.
- In a small bowl, mix together the ketchup and Worcestershire sauce. Spread this mixture over the top of the meatloaf.
- Bake in the preheated oven for 25 minutes.
- Remove the casserole from the oven and top with mashed potatoes, spreading evenly over the meat mixture.
- Sprinkle the mashed potatoes with shredded cheddar cheese and crumbled bacon.
- Return to the oven and bake for an additional 15 minutes, or until the cheese is melted and bubbly.
- Remove from the oven and allow to cool slightly before sprinkling with chopped green onions.
- Slice and serve warm.

Nutritional Information
The Cheesy Loaded Meatloaf Casserole is a deliciously filling dish, but it's important to be mindful of its nutritional content. Each serving of this casserole contains approximately 400 calories, 25 grams of fat, 25 grams of protein, and 20 grams of carbohydrates.
The ground beef provides a good source of protein, which is essential for muscle repair and growth. Cheese adds calcium and other essential nutrients, but also adds to the fat content of the dish.
It's recommended to use lean ground beef and reduced-fat cheese options if you’re watching your caloric intake. The mashed potatoes contribute to the carbohydrate content, providing energy but also adding to the overall calorie count. To learn more about the nutritional benefits and concerns of different foods, visit Nutrition.gov.
Wine/Beverage Pairings With Cheesy Loaded Meatloaf Casserole
A rich and hearty dish like Cheesy Loaded Meatloaf Casserole pairs beautifully with a full-bodied red wine such as a Cabernet Sauvignon or a Merlot. The robust flavors of these wines complement the savory and cheesy elements of the casserole perfectly.
If you prefer a non-alcoholic option, a sparkling water with a hint of lemon or lime can provide a refreshing contrast to the richness of the dish.
Cooking Tips and Variations
When making the Cheesy Loaded Meatloaf Casserole, consider mixing in some vegetables such as chopped bell peppers or mushrooms into the meat mixture for added flavor and nutrients. For a spicy kick, add a teaspoon of chili powder or a dash of hot sauce to the meat mixture.
Using a mixture of ground beef and ground pork can provide a richer flavor profile. If you prefer a lower-carb version, substitute mashed cauliflower for the mashed potatoes. Ensure the meatloaf is fully cooked by using a meat thermometer; it should reach an internal temperature of 160°F (71°C).
When serving, pair the casserole with a fresh salad or steamed vegetables to balance the meal. For an extra cheesy experience, add a layer of mozzarella or Parmesan cheese along with the cheddar.

Serving Suggestions
Cheesy Loaded Meatloaf Casserole is best served hot, straight from the oven. As the cheese bubbles and the aromas fill your kitchen, this dish invites everyone to the table.
For a well-rounded meal, consider serving the casserole with a side of roasted vegetables or a crisp garden salad drizzled with a light vinaigrette. This not only adds a splash of color to your plate but also balances the richness of the casserole with freshness.
For a more indulgent experience, consider serving with buttery garlic bread, which complements the savory flavors of the meatloaf. This dish is also versatile enough to serve at both casual family dinners and more formal gatherings, making it a go-to recipe for any occasion.
When plating, garnish with a sprinkle of fresh herbs, like parsley or chives, for an added touch of elegance.
Cheesy Loaded Meatloaf Casserole Health Benefits
While the Cheesy Loaded Meatloaf Casserole is undeniably delicious, it's important to consider its health implications. The dish is rich in protein and essential nutrients from the cheese and meat, which are beneficial for muscle and bone health.
However, it's also high in saturated fats and calories, which can be a concern for those managing cholesterol levels or trying to maintain a healthy weight. Incorporating more vegetables into the dish can increase fiber content, aiding in digestion and increasing satiety.
Opting for reduced-fat cheese and lean meats can help reduce the overall fat content. It's about finding balance; enjoying this casserole as part of a varied diet can allow you to indulge in its comforting flavors without compromising your health.
For further insights into maintaining a balanced diet, consider visiting EatRight.org.
FAQs About Cheesy Loaded Meatloaf Casserole
Can I prepare the Cheesy Loaded Meatloaf Casserole in advance?
Yes, you can prepare the meatloaf mixture and store it in the refrigerator up to a day in advance. Add the mashed potatoes and cheese just before baking.
Can I freeze leftovers?
Absolutely. Allow the casserole to cool completely, then wrap it tightly in plastic wrap or aluminum foil and freeze for up to 3 months. Thaw in the refrigerator before reheating.
What can I use instead of mashed potatoes?
Mashed cauliflower is a great low-carb alternative that still provides a creamy texture without the higher carbohydrate content of potatoes.
The Cheesy Loaded Meatloaf Casserole is a delightful dish that melds the traditional flavors of meatloaf with the comforting embrace of a casserole. It offers a versatile and satisfying meal option that can be tailored to suit various dietary needs and preferences. Whether you're cooking for a family dinner or hosting friends for a cozy gathering, this casserole is sure to impress with its savory richness and cheesy goodness. Enjoy the warmth and nostalgia of this classic dish, knowing that with a few mindful adjustments, it can fit into a balanced and nutritious diet.